Publications

BOLD

Principal Investigator

Graduate Student

Undergraduate Student

Cortical-amygdalar circuit dysfunction in a genetic mouse model of depression

K. Dzirasa, S. Kumar, B.D. Sachs, M.G. Caron, M.A.L. Nicolelis

Journal of Neuroscience.

March 6, 2013.

Chronic antidepressant treatment exacerbates serotonin deficiency in humanized tph2 mutant mice

W.B. Siesser, B.D. Sachs, A.J. Ramsey, T.D. Sotnikova, J.M. Beaulieu, X. Zhang, M.G. Caron, R.R. Gainetdinov

ACS Chemical Neuroscience.

October 1, 2012.

The p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

B. Baeza-Raja, P. Li, N. Le Moan, B.D. Sachs, C. Schachtrup, D. Davalos, E. Vagena, D. Bridges, C. Kim, A.R. Saltiel, J.M. Olefsky, K. Akassoglou

Proceedings of the National Academy of Sciences of the United States of America (PNAS).

March 28, 2012.

Pharmacological blockade of a β2AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model

M. Hara, B.D. Sachs, M.G. Caron, R.J. Lefkowitz

Cell Cycle.

January 15, 2012.

Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice

J.P. Jacobsen, W.B. Siesser, B.D. Sachs, S. Peterson, M.J. Cools, V. Setola, J.H. Folgering, G. Flik, M.G. Caron

Molecular Psychiatry.

May 3, 2011.

p75 Neurotrophin Receptor Regulates Agonist-induced Pulmonary Vasoconstriction

M. Xu, C.V. Remillard, B.D. Sachs, A. Makino, O. Platoshyn, W.H. Dillmann, K. Akassoglou, J.X.-J. Yuan

American Journal of Physiology – Heart and Circulatory Physiology.

October 1, 2008.

Regulation of cAMP by the p75 neurotrophin receptor: insight into drug design of selective phosphodiesterase inhibitors

B.D. Sachs, K. Akassoglou

Biochemical Society Transactions.

November 1, 2007.

Fibrinogen inhibits neurite outgrowth via β3 integrin-mediated transactivation of the EGF receptor

C. Schachtrup, P. Lu, L.L. Jones, J.K. Lee, J. Lu, B.D. Sachs, B. Zheng, K. Akassoglou

Proceedings of the National Academy of Sciences of the United States of America (PNAS).

July 10, 2007.

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

B.D. Sachs, G.S. Baillie, J.R. McCall, M.A. Passino, C. Schachtrup, D.A. Wallace, A.J. Dunlop, K.F. MacKenzie, E. Klussmann, M.J. Lynch, S.L. Sikorski, T. Nuriel, I. Tsigelny, J. Zhang, M.D. Houslay, M.V. Chao, K. Akassoglou

Journal of Cell Biology.

June 18, 2007.

Fibrin mechanisms and functions in nervous system pathology

R.A. Adams, M. Passino, B.D. Sachs, T. Nuriel, K. Akassoglou

Molecular Interventions.

June 1, 2004.